| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
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Specification Report
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Inspection Criteria |
Corporate Inner Quality Standard & Volume IV of C.P(2015 version) |
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Inspection Items |
Standard |
Inspection Result |
Conclusion |
|
Description |
White or off-white crystalline powder |
Off-white crystalline powder |
Conforms |
|
Identification |
IR |
Conforms |
Conforms |
|
Loss on drying |
≤0.3% |
0.16% |
Qualified |
|
Residue on ignition |
≤0.1% |
0.06% |
Qualified |
|
Single impurity |
≤0.5% |
0.23% |
Qualified |
|
Total impurities |
≤1.0% |
0.57% |
Qualified |
|
Purity(HPLC) |
≥99.0% |
99.43% |
Qualified |
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Conclusion |
According with the standard, it conformed. |
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What's Candesartan Cilexetil?
Candesartan cilexetil is a prodrug of the potent, long-acting, and selective angiotensin II type 1 receptor (AT1) antagonist, candesartan. It is rapidly hydrolyzed to candesartan during gastrointestinal absorptio. Candesartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular and the adrenal gland. Its action is, therefore, independent of the pathways for angiotensin II synthesis. Candesartan has much greater affinity ( > 10,000-fold) for the AT1 receptor than for the AT2 receptor.
Function
1.Candesartan is in a class of drugs called angiotensin II receptor antagonists. Candesartan prevents the constriction (narrowing) of blood vessels (veins and arteries).
2.Candesartan is used to treat high blood pressure (hypertension).
3.Candesartan may also be used for purposes other than those listed in this medication guide.
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