| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Specification of Analysis
| ITEM | SPECIFICATION | RESULTS |
| Color | White to off white color powder | Complies |
| Chloride test | Should be positive | Complies |
| Specification rotation | 115 °~ +125° | +120.52° |
| Water content by KFR | ≤1.0% w/w | 0.13%w/w |
| Sulphated ash | ≤0.1% w/w | 0.06%w/w |
| Heavy Metals | ≤10ppm | 5ppm |
| Relative Substances | ||
| Thiop hene amine impurity | ≤0.15% | N.D. |
| Naphthol impurity | ≤0.15% | N.D. |
| Max single impurity | ≤0.1% | 0.02% |
| Total impurity | ≤1.0% | 0.03% |
| Assay(HPLC) | 98.0% ~ 102.0% | 101% |
Duloxetine hydrochloride is the salt form of antidepressant drug duloxetine.Its pharmacological effect is the same as duloxetine. It is a new kind of selective dual inhibitor of 5 hydroxy trptamine (5-HT) and norepinephrine reuptake, and thus having antidepressant effect, while also having inhibitory effect on the central pain.
1. Duloxetine hydrochloride can inhibit neuron to 5 a serotonin and norepinephrine reuptake, thus raising the two central neurotransmitter concentrations in the brain and spinal cord.
2. Duloxetine hydrochloride can be used to treat some mood disorders such as depression and anxiety symptoms and alleviate central pain such as diabetic peripheral neuropathic pain and women fibromyalgia, etc.
3.Duloxetine hydrochloride can also be applied to the urethra serotonin and norepinephrine receptors, resulting in increased urethral sphincter nervous tension and contraction ability, so the stress urinary incontinence disease treatment is effective for women.
Application
1) In the regulation of emotion and pain sensitivity plays an important role.
2) Duloxetine hydrochloride Can be used to treat some mood disorders such as depression and anxiety, and
reduce central pain such as diabetic peripheral neuropathic pain and women such as fibromyalgia.
3) For women with stress urinary incontinence disease treatment is effective.
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