Factory Supply Terbinafine HCl CAS 78628-80-5 High Purity Low Price

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >99%
• Model NO.: Frazer -Terbinafine HCl
• Appearance: White Powder
• CAS No: 78628-80-5
• Shelf Life: 2 Years
• Test Method: HPLC
• MOQ: 1kg
• Storage: Store Cool Dry Place
• Resource: Natural
• Quality Requirement: Strictly Quality Control
• Market: Worldwide
• Service: Welcome to Visit Us
• MW: 327.9
• Mf: C21h25n·HCl
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 2000kg/Month

Product Description

Factory Supply Terbinafine HCl CAS 78628-80-5 High Purity Low Price

 

Specification of Analysis

Items	Specifications	Results
Appearance	White or almost white powder	White powder
Solubility	Practically insoluble in water and in aceton, soluble in ethanol	Complies
A: IR	The infrared absorption spectrum exhibits maximum only at the same wavelengths as that of the standard sample	Complies
B:	It gives reaction of chlorides	Complies
	Impurity A NMT 0.1%	0.00%
	Impurity B NMT 0.1%	0.01%
	Impurity C NMT 0.1%	0.02%
	Impurity D NMT 0.1%	0.02%
	Any other impurity NMT0.1%	0.05%
	Total of impurity NMT 0.3%	0.15%
Loss on drying	NMT0.5%	0.15%
Sulphated ash	NMT0.1%	0.02%
Assay	99%~101% (dried substance )	99.85%

Product Description:
Terbinafine hydrochloride is an antifungal, which is highly hydrophobic and tends to accumulate in hair, skin, nails, and fatty tissue.
Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in , soluble in ethanol, and slightly soluble in water.
Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion of squalene to lanosterol, ergosterol cannot be synthesize.

Application Aera:
1. Terbinafine is mainly effective on the dermatophyte group of fungi.
2. As a 1% cream or powder, it is used topically for superficial skin infections such as jock itch (tinea cruris), athlete's foot (tinea pedis), and other types of ringworm (tinea corporis). Terbinafine cream works in about half the time required by other antifungals.
3. Oral 250-mg tablets are often prescribed for the treatment of onychomycosis, a fungal nail infection, typically by a dermatophyte or Candida species. Fungal nail infections are located deep under the nail in the cuticle to which topically applied treatments are unable to penetrate in sufficient amounts. The tablets may, rarely, cause hepatotoxicity, so patients are warned of this and may be monitored with liver function tests. 
4. Terbinafine hydrochloride may induce or exacerbate subacute cutaneous lupus erythematosus. Persons with lupus erythematosus should first discuss possible risks with their doctor before initiation of therapy.