| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Mebendazole |
| Appearance | White powder |
| Molecular formula | C16H13N3O3 |
| Assay | 99% |
| Shelf Life | 24 months when properly stored |
| Storage | Keep in cool location |
Mebendazole or MBZ is a benzimidazole drug.
Mebendazole is used to treat infestations by worms including pinworms, roundworms, tapeworms, hookworms, and whipworms.Mebendazole (MBZ), a benzimidazole carbamate drug, was synthesized and put into clinic in 1971, and approved by FDA in 1974. It is suitable for repelling intestinal parasitic infection, blocking the formation of the microtubule system of parasitic cells, stalling the cell cycle at G2/M stage, and affecting cell mitosis. It has the characteristics of wide spectrum, high efficiency and high safety.
Mebendazole is a broad-spectrum deworming drug, which can completely kill the eggs of hookworm and whipworm and partially kill the eggs of ascaris. Mebendazole has a strong affinity for the β-tubulin of the worm and can bind to it at very low concentrations.
Application:
Mebendazole is thought to work by selectively inhibiting the synthesis of microtubules in parasitic worms, and by destroying extant cytoplasmic microtubes in their intestinal cells: thereby blocking the uptake of glucose and other nutrients, resulting in the gradual immobilization and eventual death of the helminths.
The drug is a highly effective broad spectrum antihelminitic indicated for the treatment of nematode infestations, including round worm, whip worm, thread worm, and hook worm. It is poorly absorbed and has no systemic effects.
Certification of analysis
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Items
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Requirements
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Results
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Appearance:
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White to Off-white powder
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White to Off-white powder
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Identification
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A. IR B. HPLC |
Conforms
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Loss on drying
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≤0.5%
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0.1%
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Identification A
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IR spectrum corresponds to the reference chloramphenicol standard
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Conforms
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Related Substance
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Individual impurity ≤1.0% Total impurity ≤2.0% |
0.1% 0.7% |
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Heavy metal Pb : Cadmi.um(Cd) : As : Hg: |
≤ 10ppm <1 ppm <0.5 ppm <10ppm < 1 ppm |
<10ppm Conforms 0.3ppm Conforms Negative |
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Residue on ignition
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≤0.2%
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0.04%
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Assay (HPLC)
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98.0%~102.0%
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99.3%
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Conclusion:
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The product conforms to BP.
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| Product name | Cas Number |
| Ivermectin | 70288-86-7 |
| Albendazole | 54965-21-8 |
| Florfenicol | 73231-34-2 |
| Dimetridazole | 551-92-8 |
| Levamisole | 14769-73-4 |
| Tetramisole Hcl | 5086-74-8 |
| Enrofloxacin Hcl | 112732-17-9 |
| Mebendazole | 31431-39-7 |
| Toltrazuril | 69004-03-1 |
| Praziquantel/Biltricide | 55268-74-1 |
| Fenbendazole | 43210-67-9 |
| Diclazuril | 101831-37-2 |
| Azithromycin | 83905-01-5 |
| Metronidazole | 443-48-1 |
| Nifedipine | 39562-70-4 |
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