Hot Selling Microcrystalline Cellulose 99% Food Additive

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >99%
• Model NO.: Frazer-Microcrystalline Cellulose
• Appearance: White Powder
• CAS No: 9004-34-6
• Shelf Life: 2 Years
• Test Method: HPLC
• MOQ: 1kg
• Storage: Store Cool Dry Place
• Resource: Natural
• Quality Requirement: Strictly Quality Control
• Character: Milky White Powder
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 1000kg/Month

Product Description

Hot Selling Microcrystalline Cellulose 99% Food Additive

Product Description

Microcrystalline Cellulose, white powder, revolutionized tableting because of its unique compressibility and carrying capacity. It exhibits excellent properties as an excipient for solid dosage forms. It compacts well under minimum compression pressures, has high binding capability and creates tablets that are extremely hard, stable, yet disintegrate rapidly. Other advantages include low friability, inherent lubricity, and the highest dilution potential of all binders. These properties make Microcrystalline Cellulose particularly valuable as a filler and binder for formulations prepared by direct compression, although it is also used in wet or dry granulation.

Microcrystalline cellulose functions

In the pharmaceutical industry, microcrystalline cellulose is commonly used as an adsorbent, suspending agent, diluent, disintegrant. Microcrystalline cellulose is widely used in pharmaceutical preparations, mainly used as diluents and binders in oral tablets and capsules, not only for wet granulation but also for dry direct compression. There is also some lubrication and disintegration, very useful in tablet preparation.
In the field of cosmetics, MCC as a material for a variety of cosmetics, skin treatment and care products, and cleaning detergent manufacturing.

Microcrystalline cellulose application

Filler: Fillers are mandatory for tablet manufacturing where the doses of drugs are very low. MCC can be used for all types of tablet making processes like direct compression, wet granulation, and dry procession.

Direct Compression: MCC is used as an excipient in direct compression. It has high dilution capacity and higher active ingredient carrier capacity. It has the potential to hold itself together even under direct compression. Another reason for its popularity is the low bulk density; it will lead to high dilution and packing density. It helps in producing tablets with better hardness levels and less fragile. It also provides superior white color and provides stability.

Wet granulation: As mentioned earlier it has insoluble properties at the same time it is hydrophilic. Hence, it is preferred choice for this manufacturing process. The benefit of using MCC is that can retain water, it further helps in uniform granulation. Case solidifying is a process saw in deficiently dried granules. Now and again, when the granules are dried at a high temperature, within the granules stay wet also; the surface appears to be dried. MCC is useful as it is less sensitive to wet mass, therefore, it does not get over wet, dries faster, you will find fewer case hardening and disintegrates quickly.

Roller Compaction: Roller compaction is a dry procedure including compaction of materials into strips that are at that point processed to produce a granulation. This granulation is then greased up and packed on a tablet machine. Usage of MCC in this manufacturing process improves in compaction, flow enhancement, and content uniformity.

Binder: To gain the appropriate mechanical strength and give volume to the smaller active ingredient dose, binders are very helpful. It affects the quality and appearance of the tablet. Considering the hydrophyllic water wicking qualities of MCC, it is widely used as a binder in the pharmaceutical industry.

Disintegrant: MCC is broadly utilized as a disintegrant in dry compressions also, wet granulation systems. It improves tranquilize disintegration by speeding tablet deterioration, gives the largest amount of breaking down power at low utilize levels, and uses double breaking down instruments of wicking and swelling for more quick breaking down.

Specification of Report

Batch No.	F20201111	REP DATE	NOV.11,2020
Specifications	200g/bag	MFG DATE	NOV.05,2020
Quantity	3000kg	EXP DATE	NOV.04,2023
Tests		Standard USP40	Examinations
Identification		Positive	Positive
PH		5.0-7.5	6.6
Ether-soluble Matter(%)		≤0.05	0.03
Water-soluble Matter(%)		≤0.25	0.15
Conductivity(µS/cm)		≤75	24
Residue on Ignition(%)		≤0.1	0.09
Bulk Density(g/ml)		0.32-0.42	0.375
Loss on Drying(%)		≤7.0	4.50
Particle Size: +60Mesh(%) +200Mesh(%)		≤1% ≤30%	Complies
Microbial Count		Complies	Conforms
Conclusion		It conforms to USP40.