GMP Manufacture High Quality 99% Purity Crude Meropenem CAS 96036-03-2

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: Frazer-Meropenem
• Suitable for: Animals
• State: White Powder
• Purity: >99%
• Appearance: White Powder
• CAS No: 96036-03-2
• Shelf Life: 2 Years
• Test Method: HPLC
• MOQ: 1kg
• Storage: Store Cool Dry Place
• Resource: Natural
• Quality Requirement: Strictly Quality Control
• Market: Worldwide
• Service: Welcome to Visit Us
• Delivery Time: 7-10days
• Grade: Animal Grade
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 1200kg/Month

Product Description

GMP Manufacture High Quality 99% Purity Crude Meropenem CAS 96036-03-2

What is Meropenem ?

Meropenem is a β-lactam antibiotic of the carbapenem subclass that has been shown to inhibit penicillinase-negative, -positive and methicillin-susceptible staphylococci.  

Function

This compound demonstrates the ability to also affect strains of 11 species of streptococci. Mechanistic studies suggest that Meropenem's antimicrobial activity is based on its high affinity for the majority of penicillin-binding proteins, which are cell wall-synthesizing enzymes. 

Application

Meropenem is very effective because it resists inactivation by the majority of microbial LACTB (β-lactamases) as well as kidney dehydropeptidase I. Experiments have shown Meropenem to have a low toxicity profile and, in contrast to similar compounds, no central nervous system toxicity.

Meropenem is a broad-spectrumantibiotic used to treat a variety of bacterial infections. Some of these include meningitis, intra-abdominal infection, pneumonia, sepsis, and anthrax. It is given by injection into a vein. The spectrum of action includes many Gram-positive and Gram-negative bacteria (including Pseudomonas) and anaerobic bacteria. The overall spectrum is similar to that of imipenem, although meropenem is more active against Enterobacteriaceae and less active against Gram-positive bacteria. It works against extended-spectrum β-lactamases, but may be more susceptible to metallo-β-lactamases. Meropenem is frequently given in the treatment of febrile neutropenia. This condition frequently occurs in patients with hematological malignancies and cancer patients receiving anticancer drugs that suppress bone marrow formation. It is approved for complicated skin and skin structure infections, complicated intra-abdominal infections and bacterial meningitis.

COA

TEM	SPECIFICATION	METHOD REFERENCE
Appearance	white powder	Visual
Ammonium	≤200ppm	USPmonograph
Chloride	≤200ppm	USP35<221>
Sulfate	≤300ppm	USP35<221>
Iron	≤10ppm	USP35<241>
Arsenic	≤2ppm	USP35<211>
Heavy metals	≤10ppm	USP35<231>Method I
Loss on drying(3h at 105 ºC)	≤0.5%	USP35<731>
Residue on Ignition	≤0.1%	USP35<281>
Total impurities	≤2.0%	USP monograph
Assay(dry basis)	98.0% to 101.0%	USP monograph

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