China Supplier CAS1985606-14-1 Baloxavir Marboxil Powder

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >99%
• Model NO.: Frazer-Baloxavir Marboxil
• Appearance: White Powder
• Shelf Life: 2 Years
• Storage: Keep in Cool and Dry Place
• Delivery: Express 5-7 Days Arrive
• Test Method: HPLC
• Assay: 99%
• MOQ: 1kg
• Shipping Area: Worldwide/All Countries
• CAS: 1985606-14-1
• Service: Good Service
• Delivery Method: FedEx/DHL/Special Line
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 200kg Per Month

Product Description

China Supplier CAS1985606-14-1 Baloxavir Marboxil Powder

 

Specification of Analysis

Items	Standards		Results
Appearance	Off-white to white solid powder		Complies
Identification	By IR		Complies
	By HPLC		Complies
Solubility	Freely soluble in DMSO, slightly soluble in ethanol and water		Complies
Melting Point	228ºC~230ºC		228.8ºC~229.5ºC
Loss on Drying	≤ 0.50%		0.23%
Heavy Metal	≤ 10ppm		Complies
Residue on Ignition	≤ 0.10%		0.06%
Related Substances	Any single impurity: ≤0.10%		0.08%
	Total Impurities: ≤1.00%		0.22%
Assay (HPLC basis on drying)	98.0%~102.0%		99.79%
Reference Standard	In-house Standard
Conclusion	The product complied to In-house standard.
Storage	Preserve in tight,light-resistant containers in a cool place

What is  Baloxavir marboxil?

Baloxavir marboxil is a white crystalline powder. Baloxavir marboxil is a new hat-dependent endonuclease inhibitor that kills influenza viruses within 24 hours, but some symptoms can last longer. Baloxavir marboxil inhibits virus replication by different mechanisms from existing anti-flu drugs. 

Baloxavir marboxil is used to treat influenza A and influenza B infections. The drug was initially approved for marketing in Japan in February 2018, and was approved by the FDA on October 24, 2018 for the treatment of acute uncomplicated influenza patients 12 years of age and older who have symptoms for no more than 48 hours. Baloxavir marboxil is a cap endonuclease inhibitor, which has a unique mechanism of action compared with the class of neuraminidase inhibitor drugs currently used to treat influenza infections.

Fuction and Application of  Baloxavir marboxil

Baloxavir marboxil is a new hat-dependent endonuclease inhibitor that kills influenza viruses within 24 hours, but some symptoms can last longer. Baloxavir marboxil inhibits virus replication by different mechanisms from existing anti-flu drugs. Oseltamivir (tamiflu), which is snapped up during flu, Baloxavir marboxil usually takes 72 hours to work.

Unlike neuraminidase inhibitors such as oseltamivir (tamiflu), baloxavir marboxil prevents virus replication by inhibiting cap - dependent endonuclease activity of viral polymerases.

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