Bulk API GMP Tamsulosin HCl CAS No: 106463-17-6

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >99%
• Model NO.: Frazer-Tamsulosin HCl
• Appearance: White Powder
• CAS No: 106463-17-6
• Shelf Life: 2 Years
• Test Method: HPLC
• Storage: Store Cool Dry Place
• Resource: Natural
• Quality Requirement: Strictly Quality Control
• Product Name: Tamsulosin Hydrochloride
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 2000kg/Month

Product Description

Bulk API GMP Tamsulosin HCl CAS No: 106463-17-6

Items	Specification
Characteristics	White or almost white crystalline powder, Slightly soluble in water, freely soluble in for mic acid,slightly soluble in anhydrous ethanol.
Melting point	about 230°C
Identification	1) should conformed 2) specific rotation: -17.5° to -20.5° 3) examine by infrared absorption spectrophotometry,compare the spectrum obtained with reference spectrum:should meet the requirements 4) should conformed
Related substances	Method A (EP method): Largest single impurity should ≤0.1% Method B(EP method): Largest single impurity should≤0.1% Total impurities should ≤0.2%
Enantiomeric purity	≤0.1%
Heavy metals	≤20ppm
Loss on drying	≤0.5%
Sulphated ash	≤0.1%
Assay	98.5% ~ 101.0%

Tamsulosin hydrochloride is the hydrochloride form of Tamsulosin. It is a kind of medication used for the treatment of symptomatic benign prostatic hyperplasia (BPH), boosting the passage of kidney stones. It can also be used for the treatment of acute urinary retention. It is a kind of selective antagonist of alpha-1A and alpha-1B-adrenoceptros located in prostate, prostatic capsule, prostatic urethra, and bladder neck. The blockage of these receptors through Tamsulosin causes the relaxation of smooth muscles in the bladder neck and prostate.

Function of Tamsulosin HCL

Tamsulosin HCL is used for treatment of urination disorders caused by benign prostatic hyperplasia.

Application of Tamsulosin HCL

Adverse reactions
1. the spirit of nervous system: occasionally symptoms such as dizziness, a sense of faltering.
2. the circulatory system: an occasional decrease heart rate, blood pressure, and so on.
3. allergic reactions: occasionally rash, this should stop taking the medication when the symptoms occur.
4. the digestive system: occasionally nausea, vomiting, upset stomach, abdominal pain, loss of appetite, etc.
5. liver: occasionally GOT, GPT, elevated LDH.
6. other: usually reserved for nasal congestion, swelling, difficulty swallowing, tiredness, etc.