High Purity Pharmaceutical Posaconazole Powder with CAS 171228-49-2

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: Frazer-Posaconazole
• Certification: GMP, ISO 9001, USP, BP, SGS
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >98%
• CAS No.: 171228-49-2
• Test Method: HPLC
• MOQ: 1kg
• Appearance: White Powder
• Shelf Life: 2 Years
• Storage: Cool Dry Place
• Delivery: Express 5-7 Days Arrive
• Sample: Available
• Application: Pharmaceutical Grade
• Transport Package: Foil Bag
• Specification: 1kg Per Foil Bag, 10 Bags Per Carton, 25 Kg Per Dr
• Trademark: Frazer
• Origin: China
• Production Capacity: 1000kg/Month

Product Description

High Purity Pharmaceutical Posaconazole Powder with CAS 171228-49-2

Description 
Posaconazole can effectively prevent invasive fungal infections. At present, although posaconazole injection has been approved for marketing by the FDA (approved in March 2014), its status as a main preventive drug has not changed. The antifungal spectrum of echinodin drugs (caspofungin, anidulafungin, and micafungin) is narrower than that of triazole and polyene drugs.
Use
It can be used clinically for the treatment of aspergillosis, zygomycosis and fusarium disease, and can also be used for the treatment of some fluconazole-resistant Candida infections. Studies have shown that posaconazole can widely and effectively treat Hyphomycosis phalaenopsis, and improve the survival rate of patients infected with Phalaenopsis dermatitis. The effect is dose-dependent.
 
COA

Items	Specifications	Result
Appearance	Off-white to white powder	Conforms
Identification
H-NMR	Should conforms to the standard	Conforms
Chromatography	The retention time of the principal peak in the sample preparation should correspond with the retention time of the principal peak in the related substances composite solution for system suitability	Conforms
Purity (HPLC)	Purity: ≥99.5% Any single impurity: ≤0.1%	99.88% 0.082
Water content (KF)	≤0.5%	0.11%
Optical specific rotation	-27°~31°	-29.234°
Loss on drying (LOD)	≤0.5%	0.11%
Heavy metals (Pd) ICP	≤10ppm	7.1ppm
Solvent remains(GC)	Methano l: ≤3000ppm Dichloromethan e: ≤600ppm Isopropy l alcohol: ≤3000ppm Aceton e: ≤5000ppm Dimethy l sulfoxide: ≤5000ppm	50.60ppm 58.03ppm 68.29ppm 57.14ppm 3407.18ppm
Enantiomeric purity CNP-HPLC	Enantiomers: ≤0.1%	N.D
Melting point (MP)	167ºC~171ºC	168.3ºC·170.6ºC
Conclusion	Complies with the specifications.