Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product name | Colistin Sulphate |
Appearance | White loose powder |
MF | 2(C52H98N16O13).5(H2SO4) |
CAS | 1264-72-8 |
Assay | 98%MIN |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
Colistin sulfate is highly effective against strains of Escherichia coli, Pseudomonas aeruginosa, Salmonella spp.,
Haemophilus spp., Shigella spp., Pasteurella spp., Brucella spp., Aerobacter aerogenes and Bordetella bronchiseptica.
Gram positive bacteria are generally less sensitive, but there are some sensitive strains such as
Staphylococcus spp., Bacillus spp., Streptococcus pyogenes and Corynebacterium spp.
Colistin sulfate is an antibiotic polypeptide which possesses activity mainly against Gram negative bacteria, and in
veterinary medicine is used orally for the treatment or prevention of enteritis in production animals.
Function
1.A growth promoter used in Peru in poultry and pork production is sulfate colistin, an antibiotic belonging to the polymyxin group.
2.Salmonellosis is an important disease in poultry and pork production, because of the implications that arise in Public Health, the restrictions on the marketing of products from infected farms and the impact on health programs of farms. The most common clinical manifestation of this disease is enteritis, which is often presented as a bloody or profuse watery diarrhea accompanied by fever, but you can see a broad spectrum of clinical symptoms, such as acute septicemia,abortion, arthritis, necrosis on extremities and respiratory disease.
Application
1. Colistin sulfate is the basic peptide antibiotic, mainly for the prevention and treatment of susceptible infections and promote animal growth.
2. Colistin sulfate can be combined with the cell membrane lipoprotein phosphate-free, making the cell membrane surface tension decreases, increased permeability, resulting in the cytoplasm outflow of cell death.
3. Colistin sulfate has a strong inhibitory effect against gram-negative bacteria (particularly E. coli, Salmonella, Pseudomonas aeruginosa, Proteus and Haemophilus, etc.), has no effect on Gram-positive bacteria (Staphylococcus aureus and except hemolytic streptococcus outside) and fungi.
4. Colistin sulfate oral is difficult to absorb, less toxic, easy to cause drug residues, easy to produce drug resistance.
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