Veterinary Durgs CAS 177325-13-2 Levofloxacin Hydrochloride Levofloxacin HCl Powder

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Animal
• State: White Crystalline Powder
• Purity: >99%
• Model NO.: Frazer-Levofloxacin Hydrochloride
• CAS No.: 177325-13-2
• Colour: White
• Appearance: White Crystalline Powder
• Shelf Life: 2 Years
• Storage: Cool Dry Place
• Form: Powder
• Delivery: Express 5-7 Days Arrive
• Test Method: HPLC
• Assay: 98%
• MW: 397.82800
• Mf: C18h21clfn3o4
• Application: Medical Products
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 1000kg/Month

Product Description

Veterinary Durgs CAS 177325-13-2 Levofloxacin Hydrochloride/HCl Powder
 

Product name	Levofloxacin hydrochloride CAS 177325-13-2
Appearance	White crystalline powder
MF	C18H20FN3O4.HCl
Assay	HPLC 99%
Shelf Life	2 years
Storage	Keep in cool dry place

What is Levofloxacin Hydrochloride?   Levofloxacin, sold under the trade names Levaquin among others, is an antibiotic. Levofloxacin Hydrochloride is used to treat a number of bacterial infections including acute bacterial sinusitis, pneumonia, urinary tract infections, chronic prostatitis, and some types of gastroenteritis. Along with other antibiotics it may be used to treat tuberculosis, meningitis, or pelvic inflammatory disease. Levofloxacin Hydrochloride is available by mouth, intravenously,and in eye drop form.   Levofloxacin Hydrochloride Common side effects include nausea, diarrhea, and trouble sleeping. Serious side effects may include tendon rupture, tendon inflammation, seizures, psychosis, and potentially permanent peripheral nerve damage. Tendon damage may appear months after treatment is completed. People may also sunburn more easily. In people with myasthenia gravis, muscle weakness and breathing problems may worsen.The risk of use during pregnancy is low and it is probably okay during breastfeeding. Levofloxacin is a broad-spectrum antibiotic of the fluoroquinolone drug class.It usually results in death of the bacteria. It is the left sided isomer of the medication ofloxacin.

Function:

Levofloxacin is used to treat infections including: respiratory tract infections, cellulitis, urinary tract infections, prostatitis, anthrax, endocarditis, meningitis, pelvic inflammatory disease, traveler's diarrhea, tuberculosis, and plague and is available by mouth, intravenously,and in eye drop form.

Levofloxacin is used for the treatment of pneumonia, urinary tract infections, and abdominal infections. As of 2007 the Infectious Disease Society of America (IDSA) and the American Thoracic Society recommended levofloxacin and other respiratory fluoroquinolines as first line treatment for community acquired pneumonia when co-morbidities such as heart, lung, or liver disease are present or when in-patient treatment is required.Levofloxacin also plays an important role in recommended treatment regimens for ventilator-associated and healthcare-associated pneumonia.

As of 2010 it was recommended by the IDSA as a first-line treatment option for catheter-associated urinary tract infections in adults.In combination with metronidazole it is recommended as one of several first-line treatment options for adult patients with community-acquired intra-abdominal infections of mild-to-moderate severity.The IDSA also recommends it in combination with rifampicin as a first-line treatment for prosthetic joint infections.The American Urological Association recommends levofloxacin as a first-line treatment to prevent bacterial prostatitis when the prostate is biopsied.and as of 2004 it was recommended to treat bacterial prostatitis by the NIH research network studying the condition.
Levofloxacin and other fluoroquinolones have also been widely used for the treatment of uncomplicated community-acquired respiratory and urinary tract infections, indications for which major medical societies generally recommend the use of older, narrower spectrum drugs to avoid fluoroquinolone resistance development. Due to its widespread use, common pathogens such as Escherichia coli and Klebsiella pneumoniae have developed resistance. In many countries as of 2013, resistance rates among healthcare-associated infections with these pathogens exceeded 20%.
Levofloxacin is also used as antibiotic eye drops to prevent bacterial infection. Usage of levofloxacin eye drops, along with an antibiotic injection of cefuroxime or penicillin during cataract surgery, has been found to lower the chance of developing endophthalmitis, compared to eye drops or injections alone.

Application:

Levofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. Like all quinolones, it functions by inhibiting the two type II topoisomerase enzymes, namely DNA gyrase and topoisomerase IV. Topoisomerase IV is necessary to separate DNA that has been replicated (doubled) prior to bacterial cell division. With the DNA not being separated, the process is stopped, and the bacterium cannot divide. DNA gyrase, on the other hand, is responsible for supercoiling the DNA, so that it will fit in the newly formed cells. Both mechanisms amount to killing the bacterium. In this way, levofloxacin acts as a bactericide.