Good Quality Telmisartan CAS 144701-48-4 for Hypertension with Fast Delivery

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >99%
• Model NO.: Frazer-Telmisartan
• Appearance: White Powder
• Shelf Life: 2 Years
• Storage: Keep in Cool and Dry Place
• Delivery: Express 5-7 Days Arrive
• Test Method: HPLC
• Assay: 99%
• MOQ: 1kg
• Shipping Area: Worldwide/All Countries
• CAS: 144701-48-4
• Service: Good Service
• Delivery Method: FedEx/DHL/Special Line
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 200kg Per Month

Product Description

Good Quality Telmisartan CAS 144701-48-4 for Hypertension with Fast Delivery

Specification of Analysis

Items	Standards	Results
Physical Analysis
Description	White Powder	Complies
Assay	99%	Complies
Mesh Size	100 % pass 80 mesh	Complies
Ash	≤ 5.0%	2.85%
Loss on Drying	≤ 5.0%	2.65%
Chemical Analysis
Heavy Metal	≤ 10.0 mg/kg	Complies
Pb	≤ 2.0 mg/kg	Complies
As	≤ 1.0 mg/kg	Complies
Hg	≤ 0.1mg/kg	Complies
Microbiological Analysis
Residue of Pesticide	Negative	Negative
Total Plate Count	≤ 1000cfu/g	Complies
Yeast&Mold	≤ 100cfu/g	Complies
E.coil	Negative	Negative
Salmonella	Negative	Negative

Description:

Telmisartan, 4'-[(1,4'-dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid (Micardis), does not appear to bear any structuralrelationship to this class, but there is actually a great dealof overlap in the chemical architecture with other agents.

The first, and most significant, difference is the replacement of the acidic tetrazole system with a simple carboxylic acid. This acid, like the tetrazole, plays a role in receptor binding.

The second difference is the lack of a carboxylic acid near the imidazolenitrogen that also contributes to receptor binding.As with irbesartan, however, there is not a need for this groupto be acidic but, rather, to be one that participates in receptorbinding. The second ring, much like a purine basein deoxyribonucleic acid (DNA), can hydrogen bond with theangiotensin II receptor.

Usage:

Used alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus.