Hot Selling CAS 57808-66-9 99% Domperidone with Good Price

• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP, BP, SGS
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >98%
• Model NO.: Frazer-Domperidone
• CAS No.: 57808-66-9
• Test Method: HPLC
• MOQ: 1kg
• Appearance: White Powder
• Shelf Life: 2 Years
• Storage: Cool Dry Place
• Delivery: Express 5-7 Days Arrive
• Sample: Available
• Application: Pharmaceutical Grade
• Transport Package: Foil Bag
• Specification: 1kg Per Foil Bag, 10 Bags Per Carton, 25 Kg Per Dr
• Trademark: Frazer
• Origin: China
• Production Capacity: 1000kg/Month

Product Description

Hot Selling CAS 57808-66-9 99% Domperidone with Good Price

Description:
Domperidone is a peripheral, specific blocker of dopamine receptors. It is administered orally, rectally, or intravenously. Domperidone is given in order to relieve nausea and vomiting; to increase the transit of food through the stomach (as a prokinetic agent through increase in gastrointestinal peristalsis); and to increase lactation (breast milk production) by release of prolactin. It is also used in the scientific study of the way dopamine (an important neurotransmitter) acts in the body.

Application:

There is some evidence that domperidone has antiemetic activity. Domperidone is used, together with metoclopramide, cyclizine, and 5HT3 receptor antagonists (such as granisetron) in the treatment of nausea and vomiting.

It can be used in patients with Parkinson's disease because, unlike metoclopramide, domperidone does not cross the blood-brain barrier.

Domperidone has also been found effective in the treatment of gastroparesis, a stomach motility condition, and for paediatric gastroesophageal reflux (infant vomiting).

In Canada, the drug is indicated "for the symptomatic management of upper gastrointestinal motility disorders associated with chronic and subacute gastritis and diabetic gastroparesis." The drug may also be used "to prevent gastrointestinal symptoms associated with the use of dopamine agonist antiparkinsonian agents".

COA:

Items	Requirements	Results
Appearance	White to off white powder	White powder
Solubility	Practically insoluble in water, soluble in dimethylformamide, slightly soluble in ethanol(96%) and in methanol	Confirms
Identification	A. M.P. 244~248ºC	244.5~245.5ºC
	B. IR should comply	Confirms
	C. TLC should comply	Confirms
	D. It gives the reaction of non-nitrogen substituted barbiturates.	Confirms
Clarity of solution	The solution is clear and not more intensely colored than reference solution Y6	Confirms
Related substance	Total impurities≤0.5%	≤0.29%
	Individual impurity≤0.25%	≤0.18%
Loss on drying	≤0.5%	0.07%
Sulphated ash	≤0.1%	≤0.05%
Heavy metal	≤20ppm	<20ppm
Assay	99.0%~101.0%	99.49%
Conclusion: This product conforms to the EP7.0 detection.