| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Product Description
What is St John's Wort Extract?
St John's Wort Extract was initially believed that the anti-depressant pharmacological activity of hypericin was due to inhibition of monoamine oxidase enzyme. The crude extract of Hypericum is a weak inhibitor of MAO-A and MAO-B. Isolated hypericin does not display this activity, but does have some affinity for NMDA receptors.[citation needed] This points in the direction that other constituents are responsible for the MAOI effect. The current belief is that the mechanism of antidepressant activity is due to the inhibition of reuptake of certain neurotransmitters. The large chromophore system in the molecule means that it can cause photosensitivity when ingested beyond threshold amounts.[citation needed] Photosensitivity is often seen in animals that have been allowed to graze on St. John's Wort. Because hypericin accumulates preferentially in cancerous tissues, it is also used as an indicator of cancerous cells. In addition, hypericin is under research as an agent in photodynamic therapy, whereby a biochemical is absorbed by an organism to be later activated with spectrum-specific light from specialized lamps or laser sources, for therapeutic purposes. The antibacterial and antiviral effects of hypericin are also believed to arise from its ability for photo-oxidation of cells and viral particles.
Function&Application
Function of St John's Wort Extract
St John's Wort Extract for avian influenza, atypical Newcastle disease, spread, throat, bursa of Fabricius, duck plague, duck viral hepatitis, egg drop syndrome and other viral diseases. St John's Wort Extract for poultry cold caused by high fever, difficulty breathing, cough, head and face swelling, crown purple, lack of energy, decreased intake, decreased egg production, deformed eggs more embolism. St John's Wort Extract for swine fever, blue ear disease, parvovirus, viral enteritis, infectious gastroenteritis and immune dysfunction and so on. St John's Wort Extract in vivo, in vitro are the role of retrovirus, with a strong anti-viral effect. On AIDS (HIV) early replication has a strong inhibitory effect. Can cause cancer cell programmed death, with anti-cancer effect. Can activate mononuclear phagocytic cells with enhanced immune function.
Certificate of Analysis of Hypericum Perforatum Extract
| Item |
Specification |
Result | Method |
| Maker Compounds | 0.3% Hypericin | 0.31% | HPLC |
| Identification | Complies by TLC | Complies | TLC |
| Organoleptic | |||
| Appearance | Fine Powder | Fine Powder | Visual |
| Color | Black-Brown | Black-Brown | Visual |
| Odor | Characteristic | Characteristic | Organoleptic |
| Taste | Characteristic | Characteristic | Organoleptic |
| Part Used | Whole Plant | N/A | N/A |
| Method of Extraction | Soak and Extraction | N/A | N/A |
| Extraction Solvents | Ethanol | N/A | N/A |
| Excipient | None | N/A | N/A |
| Physical Characteristics | |||
| Particle Size | NLT100%Through 80 mesh | 100% | USP <786> |
| Loss on Drying | ≤5.00% | 3.45% | Draco method 1.1.1.0 |
| Bulk Density | 40-60g/100ml | 54.5g/100ml | USP < 616> |
| Heavy metals | |||
| Residual solvent ehanol | <5000ppm | <10ppm | GC |
| Irradiation detection | Not irradiated(PPSL<700) | 329 | PPSL(CQ-MO-572) |
| Allergen detection | Non ETO Treated | Complies | USP |
| Heavy metals(as Pb) | USP standards(<10ppm) | <10ppm | USP <231> |
| Arsenic (As) | ≤3ppm | 4.32ppm | ICP-OES(CQ-MO-247) |
| Lead (Pb) | ≤3ppm | 1.02ppm | ICP-OES(CQ-MO-247) |
| Ca-dmium(Cd) | ≤1ppm | 1.210ppm | ICP-OES(CQ-MO-247) |
| Me-rcury(Hg) | ≤0.1ppm | 0.110ppm | ICP-OES(CQ-MO-247) |
| Pesticide Residue | Non-detected | Non-detected | USP <561> |
| Microbiological Tests | |||
| Total Plate Count | NMT1000cfu/g | 770 cfu/g | FDA-BAM |
| Total Yeast & Mold | NMT100cfu/g | 60cfu/g | FDA-BAM |
| E.Coli | Negative | Negative | FDA-BAM |
| Salmonella | Negative | Negative | FDA-BAM |
| Storage | Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation. |
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