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Bifonazole is an imidazol antifungal drug. Bifonazole is marketed by Bayer under the trade mark Canespor in ointment form.
Bifonazole has dual mode of action.It blocks transformation of 24-methylendihydrolanosterol to desmethylsterol in fungitogether with inhibition of HMG-CoA. This enables fungicidal properties against dermatophytes and distinguishes bifonazole from other antifungal drugs.Canesten bifonazole once daily cream contains the active ingredient bifonazole, which is an antifungal medicine. It is used to treat athlete's foot, which is a skin condition caused by infection with fungi.
Bifonazole kills the fungi that are causing the infection by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol causes holes to appear in the fungal cell membrane.
The cell membranes of fungi are vital for their survival. They keep unwanted substances from entering the cells and stop the contents of the cells from leaking out. As bifonazole causes holes to appear in the cell membranes, essential constituents of the fungal cells can leak out. This kills the fungi and treats the infection.