98% Veterinary Medicine CAS 217500-96-4 Tulathromycin for Animals

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >99%
• Model NO.: Frazer-Tulathromycin
• Appearance: White Powder
• CAS No: 217500-96-4
• Shelf Life: 2 Years
• Test Method: HPLC
• MOQ: 1kg
• Storage: Store Cool Dry Place
• Resource: Natural
• Quality Requirement: Strictly Quality Control
• Market: Worldwide
• Service: Welcome to Visit Us
• Delivery Time: 7-10days
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 2500kg/Month

Product Description

98% Veterinary Medicine CAS 217500-96-4 Tulathromycin for Animals

Tolamycin is a broad-spectrum antibacterial agent that has antibacterial activity against some Gram-positive and Gram-negative bacteria, especially for bovine and porcine respiratory diseases, such as Actinobacillus pleuropneumoniae, hemolytic Pasteur. Bacteria, Pasteurella hemorrhagic, Mycobacterium for sleep (Histophilus sleep), Mycoplasma pneumoniae, Haemophilus parasuis, Bordetella bronchiseptica, and the like.

Function of Tulathromycin 

Tulathromycin is a macrolide antibiotic used to treat bovine respiratory disease (BRD) in cattle and swine respiratory disease in pigs.

Clinical effectiveness of tulathromycin 217500-96-4, a novel triamilide antimicrobial, for the control of respiratory disease in cattle at high risk for developing bovine respiratory disease.

Application of Tulathromycin 

The efficacy of tulathromycin 217500-96-4 in decreasing the incidence of morbidity and mortality due to bovine respiratory disease (BRD) in 1,239 high-risk cattle was investigated at four US feedlots. Calves not exhibiting clinical signs of BRD received one of three treatments administered subcutaneously in the neck: physiologic saline at 0.02 ml/kg, tulathromycin 217500-96-4 at 2.5 mg/kg, or tilmicosin at 10 mg/kg. Each treatment group consisted of 413 calves. Calves with clinical signs of BRD and rectal temperatures of 104 degrees F or higher on days 1 through 14 were considered treatment failures (BRD morbidity). Nasopharyngeal swabs from saline-treated morbidities were submitted for isolation and identification of BRD organisms. Respiratory disease morbidity was highest in calves treated with saline and significantly (P < or = .0001) lower in calves administered tulathromycin 217500-96-4 or tilmicosin. Morbidity from BRD was significantly (P < or = .0001) higher in calves treated with tilmicosin than in calves treated with tulathromycin 217500-96-4. Under conditions of this study, tulathromycin 217500-96-4, given to calves at high risk of developing BRD, was significantly more effective in reducing BRD morbidity when compared to both saline- and tilmicosin-treated calves.

COA

TEST	SPECIFICATION		RESULTS
Appearance	White or off white powder		White powder
Solubility	Not soluble in water,soluble in ethanol		Conform
Assay(HPLC)	95.0%-103.0%		98.9%
Optical rotation	Between -22°and -26°at 589 nm and 25°C, from the 40mg/ml concentration of a'cetonitrile solution		-23.3°
Identification	The retention time of major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay		Conform
Residual solvents	Contain not more than 600ppm of m'ethylene chloride(CH2Cl2)		Conform
	Contain not more that 5000ppm of n-h'eptane(C7H16)		Conform
Moisture	Not more than 0.50%		0.40%
Heavy Metals	Not more than 20ppm		Conform
Related substances	Individually: Not more than 3.0%		1.0%
	Total: Not more than 6.0%		2.9%
Residue on ignition	Not more than 0.20%		0.04%
CONCLUSION	Complies with EP standards

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