CAS 98079-52-8 Lomefloxacin Hydrochloride Powder Best Price Lomefloxacin HCl

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >99%
• Model NO.: Frazer-Lomefloxacin Hydrochloride
• Appearance: White Powder
• CAS No: 98079-52-8
• Shelf Life: 2 Years
• Test Method: HPLC
• Storage: Store Cool Dry Place
• Resource: Natural
• Quality Requirement: Strictly Quality Control
• Market: Worldwide
• Service: Welcome to Visit Us
• MW: 387.81
• Melting Point: 290-300°c
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 2000kg/Month

Product Description

Best Price Provide CAS 98079-52-8 Lomefloxacin Hydrochloride Powder

Specification of Analysis

Item	Specification	Results
Appearance	White crystalline powder	White crystalline powder
Specific rotation	-94 to -99°	-95°
Identification	IR/HPLC	Conforms
PH	6.8-7.6	7.3
Clarity of solution	Should be clear	Clear
Appearance of solution	The absorbance at 450nm is not more than 0.05	0.01
Dextroisomer	≤ 0.7%	0.23%
Water	2.1%-2.7%%	2.5%
Residue on ignition	≤ 0.1%	0.02%
Heavy metals	≤ 10ppm	Conforms
Bacterial endotoxin	0.625EU/mg	Conforms
Related substances	Total impurities≤ 0.5% Other individual impurity≤ 0.2%	0.21% 0.11%

Lomefloxacin hydrochloride is the hydrochloride form of Lomefloxacin. Lomefloxacin is a bactericidal fluoroquinolone agent that is active against gram-negative and gram-positive organisms. Lomefloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase is thought to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV is thought to be the primary target in gram-positive organisms. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited. Lomefloxacin can be used to treat many kinds of infections such as respiratory, urinary tract, obstetric, gynaecological, joint, skin, oral, ear, nose, throat and eye infections. Compared with other quinolone antibacterial drugs, lomefloxacin has certain advantages such as convenient administration and no necessity of theophylline dosage adjustment.

Function

1. Lomefloxacin hydrochloride is a fluorinated quinolone antibacterial. 
2. Lomefloxacin hydrochloride is a DNA gyrase antagonist.
3. Lomefloxacin hydrochloride is also used to prevent urinary tract infections prior to surgery. 
4. Lomefloxacin hydrochloride is associated with phototoxicity and central nervous system adverse effects.