| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
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| Item | Specification | Result |
| Characteristic | A white or almost white powder | Almost white powder |
| Solubility | Practically insoluble in water,in alcohol, It shows polymorphism |
conforms |
| Infrared Absorption | Comform to the spectrum obtained from Mebendazole RS |
conforms |
| Related substances | Impurity G not more than 0.5% Any other individual impurity not more than 0.25% Total impurities not more than 1.0% |
<0.05% <0.05% <0.05% |
| Loss on drying | Not more than 0.5% | 0.06% |
| Residue on ignition | Not more than 0.1% |
0.06% |
| Partical size distribution | Particals smaller than 20um should be no less than 90% |
conforms |
| Assay | It contains not less than 99.0% and not more than 101.0% of C16H13N3O3 calculated on the dried basis |
99.8% |
| Conclusion | The quality of the above commodity complies with the standard of BP2008 and in-house specification. |
|
Mebendazole is a carbamate ester-amine. Amines behave as chemical bases. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.
Application:
Mebendazole is thought to work by selectively inhibiting the synthesis of microtubules in parasitic worms, and by destroying extant cytoplasmic microtubes in their intestinal cells: thereby blocking the uptake of glucose and other nutrients, resulting in the gradual immobilization and eventual death of the helminths.
The drug is a highly effective broad spectrum antihelminitic indicated for the treatment of nematode infestations, including round worm, whip worm, thread worm, and hook worm. It is poorly absorbed and has no systemic effects.
| Product name | Cas Number |
| Ivermectin | 70288-86-7 |
| Albendazole | 54965-21-8 |
| Florfenicol | 73231-34-2 |
| Dimetridazole | 551-92-8 |
| Levamisole | 14769-73-4 |
| Tetramisole Hcl | 5086-74-8 |
| Enrofloxacin Hcl | 112732-17-9 |
| Mebendazole | 31431-39-7 |
| Toltrazuril | 69004-03-1 |
| Praziquantel/Biltricide | 55268-74-1 |
| Fenbendazole | 43210-67-9 |
| Diclazuril | 101831-37-2 |
| Azithromycin | 83905-01-5 |
| Metronidazole | 443-48-1 |
| Nifedipine | 39562-70-4 |
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