High Quality Valganciclovir Hydrochloride with Good Price (CAS 175865-59-5)

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >99%
• Model NO.: Frazer-Valganciclovir Hydrochloride
• Appearance: White Powder
• CAS No: 175865-59-5
• Shelf Life: 2 Years
• Test Method: HPLC
• MOQ: 1kg
• Storage: Store Cool Dry Place
• Resource: Natural
• Quality Requirement: Strictly Quality Control
• Market: Worldwide
• Service: Welcome to Visit Us
• Delivery Time: 7-10days
• Mf: C14h22n6o5.HCl
• MW: 390.82
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 2500kg/Month

Product Description

High Quality Valganciclovir Hydrochloride with Good Price (CAS 175865-59-5)

 

Specification of Analysis

Items	Standards		Results
Appearance	White or off-white powder		Off-white powder
Identification	By HPLC		Complies
Melting Point	120ºC~130ºC		126ºC
Loss on Drying	≤1.00%		0.21%
Heavy Metals	≤ 10ppm		Complies
Sulfated Ash	≤ 0.10%		0.03%
Content	17.5%~19.5%		19.3%
Arsenic Content	≤ 0.1ppm		0.09ppm
Lead VContent	≤ 3.0ppm		0.50ppm
Content	≤ 0.1ppm		0.10ppm
Content	≤ 0.1ppm		0.10ppm
Microbiological Test	Coliforms:Negative		Negative
	Salmonella: Negative		Complies
	Total plate count: ≤1000 CFU/g		Pass
	Yeast&Mold: ≤50 CFU/g		Pass
Related Substances	Impurity A: ≤0.30%		0.18%
	Other unknown impurity: ≤0.10%		0.07%
	Total Impurities: ≤0.50%		0.42%
Assay	≥ 98.0%		99.50%
Reference Standard	USP Standard
Conclusion	The product complied to USP standard.
Storage	Preserve in tight,light-resistant containers in a cool place

What is Valganciclovir hydrochloride?
Valganciclovir is a DNA polymerase inhibitor. After oral administration, ganciclovir is rapidly hydrolyzed into ganciclovir under the action of intestinal mucosal cell esterase and liver esterase, so its pharmacodynamic characteristics are the pharmacodynamic characteristics of ganciclovir. Ganciclovir can produce ganciclovir triphosphate by enzymatic phosphorylation in virus and cell, which competes with deoxyguanosine triphosphate (dGTP) as the substrate of viral DNA polymerase, thus inhibiting the synthesis of viral DNA and producing anti-CMV activity.
 

Application of Valganciclovir hydrochloride:

Is used for preventing and treating CMV infection secondary to organ transplant recipients. This drug is a prodrug of ganciclovir, and it is an active valine ester of ganciclovir. After oral administration, it can be rapidly hydrolyzed into ganciclovir by phosphatase in intestinal and liver cells. Its antiviral spectrum and action mechanism are similar to ganciclovir, but its bioavailability is significantly higher than that of ganciclovir. Its oral absorption bioavailability is 62.4%, which is 10 times that of ganciclovir, while its toxicity is greatly reduced..

Strenghths of Our Products: 

1) Living with chemical innovation;
2) Equipped with the professional quality testing equipment & conscience of the field.
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4) Highly pure and salfe and can be applied in various fields.