Wholesale Pharmaceutical Chemicasl Powder Tacrolimus Powder CAS 104987-11-3

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >99%
• Appearance: White Powder
• Shelf Life: 2 Years
• Storage: Keep in Cool and Dry Place
• Delivery: Express 5-7 Days Arrive
• Test Method: HPLC
• Assay: 99%
• Shipping Area: Worldwide/All Countries
• CAS: 104987-11-3
• Service: Good Service
• Delivery Method: FedEx/DHL/Special Line
• Product Name: Tacrolimus
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 200kg Per Month

Product Description

Wholesale Pharmaceutical Chemicasl Powder Tacrolimus Powder CAS 104987-11-3

Specification of Analysis

Product Name	Tacrolimus Powder
CAS	104987-11-3
Appearance	White fine powder
MF	C44H69NO12
MW	804.02
Assay	99%

What  is Tacrolimus ?

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug.It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription.
 

Function

1. Tacrolimus is used with other medications to prevent rejection of a kidney, heart, or liver transplant.
2. Tacrolimus is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo. 
3. Tacrolimus can be combined with steroids, azathioprine (Imuran Azasan) or mycophenolate mofetil (CellCept).