Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Item | Standard | Result | ||||
Appearance | White or off-white crystalline powder | Conforms | ||||
IR Absorption | Consist with the spectra obtained with Cimetidine CRS. | Conforms | ||||
UV Absorption | Should conform | Conforms | ||||
Melting point | 139-144°C | 140.5-141.0°C | ||||
Heavy metal | ≤20ppm | <20ppm | ||||
Residue on ignition | ≤0.2% | 0.02% | ||||
Related substances | Single impurity≤0.2% | 0.15% | ||||
Total impurity≤1.0% | 0.47% | |||||
Loss on drying | ≤1.0% | 0.06% | ||||
Organic volatile impurities (ethanol) (loss on drying) | ≤0.5% | 0.06% | ||||
Assay (calculated with reference on dried substance) | 98.0-102.0% | 99.60% |
Description:
Cimetidine is an immunomodulator and a histamine congener. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the growth of several tumors, including gastrointestinal cancer. This compound is an anti-angiogenic agent. Cimetidine is an activator of Nischarin.
Function
Used in the treatment of duodenal ulcer, gastric ulcer, upper gastrointestinal bleeding, chronic colitis, herpes zoster, disease such as chronic urticaria. Against the virus and immune enhancement have certain effect.
Application