Customization: | Available |
---|---|
Powder: | Yes |
Customized: | Customized |
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Item |
Specification |
Specific rotation |
+39.5 to +41.5° |
State of solution(transmittance) |
Clear 98.0% min. |
Chloride[cl] |
0.020% max. |
Ammonium [NH4] |
0.02% max. |
Sulfate[SO4] |
0.020% max |
Iron[Fe] |
10ppm max. |
Heavy metals [Pb] |
10ppm max |
Arsenic[As2O3] |
1ppm max |
Other amino acids |
Chromatographically not detectable |
Loss on drying |
0.20% max. |
Residue on ignition[sulfated] |
0.10% max. |
Assay |
99.0% min |
Dabigatran etexilate mesylate is a direct thrombin inhibitor used in clinical practice and a new type of oral anticoagulant. Its mechanism of action is to inhibit the formation of fibrin through reversible and strong competition to bind to the specific binding site of thrombin fibrin, thereby inhibiting the formation of thrombus.
Dabigatran etexilate mesylate is a raw material for the blood system; an anticoagulant drug; it can be used in patients with non-valvular atrial fibrillation to reduce the risk of stroke and systemic embolism; Chemicalbook dabigatran etexilate is a new type of synthetic The direct thrombin inhibitor is a prodrug of dabigatran and is a non-peptide thrombin inhibitor.
Function
Dabigatran is used to prevent strokes in those with atrial fibrillation not caused by heart valve issues, as well as deep vein thrombosis and pulmonary embolism in persons who have been treated for 5-10 days with parenteral anticoagulant (usually low molecular weight heparin), and to prevent deep vein thrombosis and pulmonary embolism in some circumstances.
It appears to be as effective as w'arfarin in preventing nonhemorrhagic strokes and embolic events in those with atrial fibrillation not due to valve problems.
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