| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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RU58841 is an androgen receptor blocker. It binds to androgen receptors with great specificity and tenacity, but does not activate the receptor. Its presence on the receptor prevents androgens such as DHT from binding to and activating the receptor. It has been extensively studied as a topical agent to treat acne and androgenetic alopecia (1, 2, 3).
Certificate of Analysis
| Item | Specifications | Results |
| Appearance | White powder | White powder |
| Identification(byHPLC) | RT of the sample should match with stand in the Related substances | Complies |
| Solubility | Very soluble in ethanol, metha nol, slightly soluble in water | Complies |
| Water | NMT 0.5% | 0.43% |
| Purity | NLT 99.0% | 99.88% |
| Specific rotation | Between + 33º to +37º | 36.80% |
| Residue on ignition | NMT 0.1% | 0.02% |
| Heavy metals | NMT 10ppm | Complies |
| 15β-bimatoprost | NMT 0.2% | Not detected |
| 15-Keto derivative | NMT 0.2% | Not detected |
| 5,6-trans Isomer | NMT 0.2% | 0.04% |
| Total other impurities | NMT 0.5% | 0.08% |
| Ethanol | NMT 0.5% | Not detected |
| Ethyl ace tate | NMT 0.5% | 0.10% |
RU58841 Description
RU58841 is the drug for the treatment of hair loss dwindled, perhaps due more to commercial potential and chemical stability reasons than efficacy as the later studies of RU58841 have focused on different chemical forms of the drug and combining it with various nanoparticles to enhance delivery.
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