Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product Name | Best quality Fusidic acid CAS 6990-6-3 |
Appearance | white powder |
Assay | 99.5% |
Certificate | ISO 9001 |
Test | HPLC |
Packing | Bag, drum |
MF | fos |
StorageTemperature | Keep in a cool, dry, dark location in a tightly sealed container or cylinder |
Fusidic acid is a bacteriostatic antibiotic that is often used topically in creams and eyedrops, but may also be given systemically as tablets or injections. The global problem of advancing antimicrobial resistance has led to a renewed interest in its use recently,
Fusidic acid is active in vitro against Staphylococcus aureus, most coagulase-negative staphylococci, Beta-hemolytic streptococci, Corynebacterium species, and most clostridium species. Fusidic acid has no known useful activity against enterococci or most Gram-negative bacteria (except Neisseria, Moraxella, Legionella pneumophila, and Bacteroides fragilis). Fusidic acid is active in vitro and clinically against Mycobacterium leprae, but has only marginal activity against Mycobacterium tuberculosis.
Application:
For drug-resistant Staphylococcus aureus infections, such as pneumonia, osteomyelitis, sepsis and so on. Severe patients need intravenous administration and should be used in combination with other anti-staphylococcal drugs. Topical treatment of skin and wound infections.
Specification of Report
Product Name | Fusidic Acid | CAS | 6990-06-3 | |
According to | EP10.4 | |||
Items | Standard | Results | ||
Appearance | White or almost white crystalline powder | white crystalline powder | ||
Solubility | Practically insoluble in water,freely Conformed Soluble in ethanol(96 percent) | Complies | ||
Identification | The infrared spectrum should be conformed with Conformed the fusidic acid CRS | Complies | ||
The residue dose not give reaction of sodium | Complies | |||
Water | 1.4%- 2.0% | 1.45% | ||
Content( anhydrous substance) | 97.5%- 101.0% | 99.8% | ||
Sulfated ash | ≤0.2% | 0.07% | ||
Related Impurity by HPLC |
Impurity M≤1.0% | 0.13% | ||
Impurity G≤0.7% | ND | |||
Impurity L≤0.5% | 0.02% | |||
Impurity B≤0.4% | ND | |||
lmpurityA≤0.3% | ND | |||
Impurity H≤0.1% | 0.02% | |||
Impurity C≤0.2% | ND | |||
Impurity D≤0.2% | ND | |||
Impurity F≤0.2% | ND | |||
Impurity l≤0.2% | ND | |||
Impurity K≤0.2% | 0.02% | |||
Impurity N≤0.2% | ND | |||
Main unspecified impurities≤0.1 % | ND | |||
Total impurities≤2 .0% | 0.18% | |||
Particle diamite<20µm | > 90% | 100% | ||
Particle diamite<30µm | 100% | 100% | ||
Residual solvents | Ethanol≤5000ppm | Complies | ||
Methano≤3000ppm | Complies | |||
N-Hexan≤290ppm | Complies |