| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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What is Adapalene?
Adapalene is a second-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions.[1] It is effective against acne conditions where comedones are predominant
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| Analysis Item | Indexes |
| Characteristics | White or almost white crystalline powder |
| Identification | IR |
| Solubility | Practically insoluble in water and ethanol, sparingly soluble in te'trahydrofuran. |
| Appearance of solution | Solution must be clear and color NMT BY6 of EP |
| Heavy metals | ≤20ppm |
| Loss on drying | ≤0.5% |
| Sulfated ash | ≤0.1% |
| Related substances | Impurity A:≤0.3% ImpurityD: ≤0.2% Impurity C:≤0.15% Unknown impurity:≤0.1% Total impurity: ≤0.5% |
| Residue solvents | Te'trahydrofuran:≤720ppm Acetic acid:≤5000ppm M'ethanol:≤3000ppm N,N-dimethyl formamide:≤880ppm |
| Assay(on dried basis) | 98.0%-102.0% |
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