High Quality Nootropics 99% Powder Pramiracetam CAS 68497-62-1

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: Frazer-Pramiracetam
• Certification: GMP, ISO 9001, USP, BP, SGS
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >98%
• CAS No.: 68497-62-1
• Test Method: HPLC
• MOQ: 1kg
• Appearance: White Powder
• Shelf Life: 2 Years
• Storage: Cool Dry Place
• Delivery: Express 5-7 Days Arrive
• Sample: Available
• Transport Package: Foil Bag
• Specification: 1kg Per Foil Bag, 10 Bags Per Carton, 25 Kg Per Dr
• Trademark: Frazer
• Origin: China
• Production Capacity: 1000kg/Month

Product Description

High Quality Nootropics 99% Powder Pramiracetam CAS 68497-62-1

 

What is Pramiracetam?
Pramiracetam (also known as Pramistar) is a cognitive enhancer (nootropic) that is synthesized from piracetam, the original racetam, by substituting the amide group in piracetam with a dipropan-2-ylamino ethyl group. This substitution allows pramiracetam to be more potent than piracetam.

Pramiracetam was developed in 1979 by Parke-Davis, a division of the Warner-Lambert pharmaceutical company. Pramiracetam was at first distributed under the brand name Pramistar. Now, it is part of Pfizer, since Warner-Lambert merged with Pfizer in 2000.

Pramiracetam is found to increase rats' object recognition with a significantly lower dose when compared to piracetam. Piracetam required 13 times the dose of pramiracetam to have the same effect.

Pramiracetam Mechanism of Action:
Acetylcholine (ACh) is a neurotransmitter involved in learning and memory. Pramiracetam increased the rate of choline uptake into the rat brain cells by 30 to 37%. Increased uptake of choline provides more choline as a source to build ACh. This effect lasts approximately 24 hours.

Even when rats were given scopolamine, a substance that reduces choline concentration in the brain, treatment with pramiracetam prevented choline depletion.
Nitricoxide is a compound that is known to play a role in memory and learning. Pramiracetam increases nitricoxide production in the brain.

The action of pramiracetam and other racetams depends on adrenal hormone availability. In rats, racetams, including pramiracetam, lost their "memory-improving effect" after the animals had their adrenal glands removed. Inhibition of adrenal hormone production also suppressed the memory-improving effects of pramiracetam in mice.
However, higher levels of adrenal hormones aldosterone or corticosterone (cortisol equivalent) also blocked the memory-improving effects of this drug in mice in a dose-related manner.

COA:

ITEM	SPECIFICATION	RESULT	METHOD
Appearance	White powder, neutral odor, highly hygroscopic	Conforms	Visual
Identification	Standard solution and test solution same spot,RF	Conforms	TLC
Specific Optical	-2.4°~ -2.8°	-2.72°
Heavy metals (as PB)	≤10ppm	Conforms	AAS
Sulfate (SO4)	≤0.02%	Conforms	Colorimetry
Chloride (Cl)	≤0.02%	Conforms	Colorimetry
Phosphate Ion (P)	≤5ppm	Conforms	Colorimetry
Residual solvent(ethanol)	≤1.0%	Conforms	HS-GC
pH	4.5~7.0	5.10
Related substance	Spot not bigger than standard solution spot	No spot	TLC
Water Content	≤2%	0.26%	KF
Assay (dried basis)	98.0%--102.0%	99.48%	Potentiometric titration
Assay (dried basis)	98.5%--100%	99.2%	HPLC

Product name	Cas Number
Ivermectin	70288-86-7
Albendazole	54965-21-8
Florfenicol	73231-34-2
Dimetridazole	551-92-8
Levamisole	14769-73-4
Tetramisole Hcl	5086-74-8
Enrofloxacin Hcl	112732-17-9
Mebendazole	31431-39-7
Toltrazuril	69004-03-1
Praziquantel/Biltricide	55268-74-1
Fenbendazole	43210-67-9
Diclazuril	101831-37-2
Azithromycin	83905-01-5
Metronidazole	443-48-1
Nifedipine	39562-70-4