| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
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Tenofovir use for transmitted diseases are pharmacologic agents and chemical substances that are capable of killing or destroying certain microorganisms that commonly cause human infection (for example, the human immunodeficiency virus).
Tenofovir are a diverse group of chemical compounds that exert their activity by a variety of different mechanisms of action. Multiple compounds are being developed and tested for their microbicidal activity in clinical trials. Microbicides can be formulated in various delivery systems including gels, creams, lotions, aerosol sprays, tablets or films and sponges and vaginal rings (or other devices that release the active ingredient(s) over a longer period).
|
Items of analysis |
Specification |
Results |
|
Appearance |
White powder or off-white powder |
White Powder |
|
Identification |
Must conform to reference standard |
Conforms |
|
Water |
NMT3.0% |
1.53% |
|
Residue on ignition |
NMT2.0% |
1.07% |
|
Specific Rotation |
-19.0°~-23.0° |
-22.5° |
|
Sulphated ash |
≤1.5% |
0.27% |
|
Single impurity |
≤1.0% |
0.29% |
|
Total impurity |
≤3.0% |
1.11% |
|
Assay(Titrimetry) |
98.0%-102% |
98.60% |
|
9-Propenyl adenine |
≤100ppm |
Conforms |
|
PMPA Monoester Impurity |
≤1.5% |
0.35% |
|
Conclusion |
Qualified |
|
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