Pharmaceutical Raw Material Ticlopidine Hydrochloride Powder CAS No 53885-35-1 Ticlopidine HCl

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >99%
• Appearance: White Powder
• Shelf Life: 2 Years
• Storage: Keep in Cool and Dry Place
• Delivery: Express 5-7 Days Arrive
• Test Method: HPLC
• Assay: 99%
• Shipping Area: Worldwide/All Countries
• CAS: 53885-35-1
• Service: Good Service
• Delivery Method: FedEx/DHL/Special Line
• Product Name: Ticlopidine Hydrochloride
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 200kg Per Month

Product Description

Pharmaceutical Raw Material Ticlopidine Hydrochloride Powder CAS No 53885-35-1 Ticlopidine HCl

Specification of Analysis

Product Name	Ticlopidine Hydrochloride Powder
CAS	53885-35-1
Appearance	white powder
Molecular formula	C14H14ClNS.ClH
Molecular Weight	300.25
Assay	98%
Shelf Life	Two years
Storage	Store in a dry, cool and sealed place

What is Ticlopidine hydrochloride?

Ticlopidine hydrochloride is an adenosine diphosphate (ADP) receptor inhibitor against platelet aggregation with IC50 of ~2 μM. Target: Adenosine diphosphate (ADP) Ticlopidine (trade name Ticlid) is an antiplatelet drug in the thienopyridine family. Ticlopidine hydrochloride inhibits platelet aggregation with IC50 of ~2 μM in men. Like clopidogrel, it is an adenosine diphosphate (ADP) receptor inhibitor. It is used in patients in whom aspirin is not tolerated, or in whom dual antiplatelet therapy is desirable. Because it has been reported to increase the risk of thrombotic thrombocytopenic purpura (TTP) and neutropenia, its use has largely been supplanted by the newer drug, clopidogrel, which is felt to have a much lower hematologic risk. Its niche role as an alternative in those patients who do not tolerate Clopidogrel has now been superdeded by Ticagrelor and Prasugrel. The usual dose is 250 mg twice daily by the oral route. Ticlopidine hydrochloride, when orally administered to rats, results in activation of basal and prostaglandin E1 (PGE1)-stimulated adenylate cylase activity through increase in affinity of the cyclase in platelet membrane to PGE1, although it failed to affect adenosine- or sodium fluoride-stimulated activity of the enzyme.

Function and Application of Ticlopidine hydrochloride 

It is used in patients in whom aspirin is not tolerated, or in whom dual antiplatelet therapy is desirable.