Supply High Purity API Powder CAS 1400-61-9 Nystatin

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Yellow Powder
• Purity: >99%
• Model NO.: Frazer-Nystatin
• CAS No.: 1400-61-9
• Appearance: Yellow Powder
• Shelf Life: 2 Years
• Storage: Store in a Well-Closed Container Away From Moistur
• Form: Powder
• Delivery: Express 5-7 Days Arrive
• Test Method: HPLC
• Assay: 99%
• Einecs: 615-996-8
• M.F.: C47h75no17
• Application: Antibiotics
• Transport Package: Foil Bag
• Specification: 1kg Per Foil Bag, 10 Bags Per Carton, 25 Kg Per Dr
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 1000kg/Month

Product Description

Supply High Purity API Powder CAS 1400-61-9 Nystatin
 

Specification of Analysis

Item	Test Standard		Testing Result
Appearance	Powder		Complies
Color	yellow Powder		Complies
Particle Size	100% pass 80 mesh		Complies
Oder	Characteristic		Complies
Taste	Characteristic		Complies
Loss on Drying	≤5.0%		2.20%
Residue on Ignition	≤0.1%		0.05%
Residual a'cetone	≤0.1%		Complies
Residual Ethanol	≤0.5%		Complies
Heave Mentals	≤10ppm		Complies
Na	≤0.1%		<0.1%
Pb	≤3 ppm		Complies
Total Plate	<1000CFU/g		Complies
Yeast & Mold	<100 CFU /g		Complies
E. Coli	Negative		Complies
Salmonella	Negative		Complies
Conclusion: Conform with USP Standard

Nystatin is a polyene antifungal drug to which many molds and yeast infections are sensitive, including Candida.

Cutaneous, vaginal, mucosal and esophageal Candida infections usually respond well to treatment with nystatin.

Like amphotericin B and natamycin, nystatin binds to ergosterol, a major component of the fungal cell membrane. When present in sufficient concentrations, it forms pores in the membrane that lead to K+ leakage and death of the fungus.

Function:

1). Nystatin is often used as prophylaxis in patients who are at risk for fungal infections.

2). It is prescribed in units, with doses varying from 100,000 (for oral infections) to 1 million (for intestinal ones). As it is not absorbed from the gut, it is safe for oral use and does not have problems of drug interactions.

3). It is also used in cellular biology as an inhibitor of the lipid raft-caveolae endocytosis pathway on mammalian cells, at concentrations around 3 µg/mL.

4). In certain cases, nystatin has been used to prevent the spread of mold on objects such as works of art. For example, it was applied to wood panel paintings damaged as a result of the Arno River Flood of 1966 in Florence, Italy.

5). Nystatin is also used as a tool by scientists performing "perforated" patch-clamp electrophysiologic recordings of cells. When loaded in the recording pipette, it allows for measurement of electrical currents without washing out the intracellular contents, because it forms pores in the cell membrane that are permeable to only monovalent ions.