Pharmaceutical Intermediates 99% CAS 388082-78-8 Lapatinib Ditosylate

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: White Powder
• Purity: >99%
• Model NO.: Frazer-Lapatinib
• Appearance: White Powder
• CAS No: 388082-78-8
• Shelf Life: 2 Years
• Test Method: HPLC
• MOQ: 1kg
• Storage: Store Cool Dry Place
• Resource: Natural
• Quality Requirement: Strictly Quality Control
• Market: Worldwide
• Service: Welcome to Visit Us
• Delivery Time: 7-10days
• Product Specifications: Pharmaceutical Grade
• MW: 925.46
• Transport Package: Foil Bag
• Specification: 99%
• Trademark: Xi′an Frazer Biotech Co., Ltd.
• Origin: China
• Production Capacity: 2500kg/Month

Product Description

Pharmaceutical Intermediates 99% CAS 388082-78-8 Lapatinib Ditosylate

Specification of Analysis

TEST ITEMS	SPECIFICATION	RESULTS
Description	white crystalline powder	white crystalline powder
Identification	IR	Positive
Assay	97.0~103.0%	99.37%
Melting Point	70~80°C	70.5~76.5°C
Specific Rotation	+22~+26°	+23.09°
Loss On Drying	0.5%max	0.25%
Residue On Ignition	0.1%max	0.05%
Heavy Metals	20PPm max	<20PPm
Organic Volatile Impurities	Meets the requirement.	Conforms
Related Substances	Single Impurity: 1.0%max	<1.0%
	Total Impurities: 2.0%max	<2.0%
Conclusion	The specification conforms to enterprise standard.

Lapatinib is used as a treatment for women's breast cancer in treatment naive, ER+/EGFR+/HER2+ breast cancer patients(now often called "triple positive") and in patients who have HER2-positive advanced breast cancer that has progressed after previous treatment with other chemotherapeutic agents, such as anthracycline, taxane-derived drugs.

Usage of Lapatinib

1.Lapatinib is a breast cancer targeted therapy drug . Breast cancer molecular targeted therapy aims at the occurrence and development of cancer-related genes and their expression products of breast cancer for treatment. Molecular targeted drugs by blocking signal transduction of tumor cells or associated cells , control changes in cell gene expression, in order to inhibit or kill tumor cells.

2.Lapatinib is a novel targeted anti-cancer drug. It Can act on Her-1 and Her-2 two targets at he same time, the biological effect of the inhibition of tumor cell proliferation and growth arising from this mode of action is much larger than acting on just one target. The so-called targeted therapy, refers to certain receptors, genes or proteins as a key target, and then targets to kill tumor cells related to drugs.

How to use lapatinib

Read the Patient Information Leaflet provided by your pharmacist before you start using lapatinib and each time you get a refill. If you have any questions, consult your doctor or pharmacist.

Take this medication by mouth 1 hour before or 1 hour after a meal, usually once daily or as directed by your doctor. It is important that you do not take this medication more than once daily.

The dosage is based on your medical condition, response to treatment, and certain other drugs you may be taking.