| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, HSE, ISO 9001, USP, BP |
| Suitable for: | Elderly, Children, Adult |
| State: | White Powder |
| Purity: | >99% |
| Samples: |
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| Customization: |
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| Product Name | HEPARIN SODIUM |
| Appearance | White to off- white powder |
| Residue on ignition | 28.0%- 41.0% |
| Nitrogen(calculated on the dried basis ) | 1.3%-2.5% |
| Heavy metals | ≤30ppm |
| Limit of galactosamine in total hexosamine | ≤1% |
| Nucleotidic impurities | Absorbance at 260nm: ≤0.20 |
Absence of oversulfated chondroitin sulfate |
A. Proceed as directed in identification test A. No features associated with oversulfated chondroitin sulfate are found between 2.12 and 3.00ppm B. No peaks corresponding to oversulfated chondroitin sulfate should be detected eluting after the heparin peak. |
| PH | 5.0-7.5 |
| Loss on drying | ≤5.0% |
| Protein impurities | ≤1.0% |
| Bacterial endotoxins test | Not more than 0.03 USPEU/USPU of Heparin |
| Not more than 0.03 USPEU/USPU of Heparin | ≥180 IU/mg |
| Residual solvents | Ethanol: ≤ 5000 ppm |
| Microbial contamination | A:Total viable aerobic count: max 10CFU/g B: Molds/yeasts |
Description:
Reviparin sodium, a second-generation low molecular weight heparin produced from porcine mucosal heparin, has been introduced for the prevention of deep vein thrombosis and pulmonary embolism following surgery. It has sustained activity and increased bioavailability over unfractioned heparin. More noticeably, reviparin shows a pronounced inhibitory effect, both in vitro and in vivo , on smooth cell proliferation which plays a predominant role in restenosis following angioplasty. Indeed, a lower incidence of restenosis without major bleeding complications has been reported for reviparin treated patients who successfully underwent percutaneous transluminal coronary angioplasty.
Usage:
1. Biochemical studies; used for preventing the conversion of prothrombin into thrombin; has blood anti-thrombosis effect.
2. For the delay and prevention of blood clotting.
3. Heparin sodium salt is a mucopolysaccharides biochemical medicine extracted from porcine small intestinal mucosa with strong anticoagulant activity. Mclcan found it from the liver tissue of dog in the study of the clotting mechanism. Brinkous et al proved that heparin having anticoagulant activity. After the first application of heparin as an anticoagulant in clinical filed, it has drawn worldwide attention. With a strong anticoagulant effect, heparin is the primary choice for prevention and treatment of deep vein thrombosis and other thrombotic diseases.
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Audited Supplier 
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